Defiance Resorts
900 ft²
4 Guests
1 Bedroom
1 Bathroom
Family Friendly
Cabin
- Fireplace/Heating
- Balcony/Terrace
- Kitchen
US $200/Night
For 7 Nights US $1,398
904.17 ft²
4 Guests
1 Bedroom
1 Bathroom
Free Cancellation
House
- Fireplace/Heating
- Parking
- Internet
US $244/Night
For 7 Nights US $1,706
1 Bedroom
1 Bathroom
Family Friendly
Hotel
- Pool
- Breakfast
- Kitchen
US $93/Night
For 7 Nights US $654
6 Guests
2 Bedrooms
2 Bathrooms
Family Friendly
House
- Hot Tub
- Fireplace/Heating
- Balcony/Terrace
US $263/Night
For 7 Nights US $1,841
1097.92 ft²
6 Guests
2 Bedrooms
1 Bathroom
Family Friendly
Apartment
- Spa
- Fireplace/Heating
- Parking
US $312/Night
For 7 Nights US $2,186
1100 ft²
2 Guests
1 Bedroom
1 Bathroom
Family Friendly
Cottage
- Hot Tub
- Fireplace/Heating
- Balcony/Terrace
US $308/Night
For 7 Nights US $2,153
947.22 ft²
6 Guests
2 Bedrooms
1 Bathroom
Family Friendly
Apartment
- Fireplace/Heating
- Parking
- Internet
US $286/Night
For 7 Nights US $2,000
375 ft²
3 Guests
1 Bedroom
1 Bathroom
Family Friendly
Apartment
- Fireplace/Heating
- Balcony/Terrace
- Kitchen
US $164/Night
For 7 Nights US $1,145
1302.43 ft²
2 Guests
1 Bedroom
1 Bathroom
Family Friendly
Apartment
- Spa
- Fireplace/Heating
- Pet Friendly
US $275/Night
For 7 Nights US $1,925
1100 ft²
6 Guests
2 Bedrooms
1 Bathroom
Family Friendly
Apartment
- Fireplace/Heating
- Balcony/Terrace
- Kitchen
US $272/Night
For 7 Nights US $1,904
904.17 ft²
4 Guests
1 Bedroom
1 Bathroom
House
- Spa
- Fireplace/Heating
- Parking
US $213/Night
For 7 Nights US $1,491
1300 ft²
2 Guests
1 Bedroom
1 Bathroom
Family Friendly
Apartment
- Fireplace/Heating
- Balcony/Terrace
- Pet Friendly
US $199/Night
For 7 Nights US $1,396
Why Choose Rent By Owner for your Defiance Resorts?
What makes our Resorts special?
Verified Listings
Book with confidence knowing every property meets our quality and safety standards.
Unbeatable Value
Enjoy competitive pricing with no hidden fees, providing exceptional value for every stay.
Diverse Options
From cozy cabins to luxurious villas, find a rental that suits your style and needs.
Weekly Weather Forecast for Defiance
How to Book Your Defiance Resorts
What's our booking process?
Our platform allows you to browse a curated selection of resorts. Once you find the ideal property, you’ll be redirected to a trusted booking partner to complete your reservation securely.
Booking Steps
01
Search Properties
Use our filters to find the right property that fits your needs.
02
Select a Rental
Click on your preferred listing to view details, amenities, and pricing.
03
Book Online
Follow the link to finalize your reservation directly on the partner’s website.
Explore and book the perfect rental in Defiance
Common Resorts Amenities
What amenities can you expect?
Our Resorts are designed to offer all the comforts of home, often with added perks to make your stay unforgettable. Here’s some common amenities to look forward to:
Indoor Features
- Fully-equipped kitchens with modern appliances
- Comfortable living areas with flat-screen TVs
- Free Wi-Fi for staying connected
- Air conditioning and heating for year-round comfort
- In-unit washers and dryers for convenience
- Luxurious bedrooms with premium bedding
- Spa-like bathrooms with soaking tubs or walk-in showers
Other Places to Stay in Defiance, MO
New Melle
August A. Busch Memorial Conservation Area
Chandler Hill Vineyards
Broemmelsiek Park
Historic Daniel Boone Home and Heritage Center
Yellow Farmhouse Winery
Sugar Creek Winery
Defiance Resorts Frequently Asked Questions
1. What are the top Resorts in Defiance?
There are a lot of options in Defiance. If you plan on staying in the Defiance area, consider making a reservation for a few nights at one of these properties as these have been rated the Top Resorts in Defiance:
- Hilton Garden Inn St. Louis/O'Fallon MO
- Holiday Inn Express St. Louis West - O'Fallon by IHG
- Staybridge Suites O'Fallon Chesterfield by IHG
- Sleep Inn & Suites O'Fallon MO - Technology Drive
- Holiday Inn Express Hotel & Suites St. Louis West-O'Fallon by IHG
- Staybridge Suites O'Fallon Chesterfield by IHG
- Vino Villa Wine Country Gem Patio and Grill
- The Cabernet Cabin Defiance Home on Katy Trail!
- The Merlot Bungalow Defiance Tiny Home on Trail
- The Chardonnay Chalet Defiance Studio Trail!
2. How many Resorts are available in Defiance?
Currently, the total number of properties listed by RBO in 2026 is over 34 in the Defiance area, and still counting. By aggregating listings from multiple websites, RBO offers an immense amount of choice of the best Resorts in Defiance.
More Rentals You May Like Near Defiance
1097.92 ft²
6 Guests
2 Bedrooms
2 Bathrooms
Apartment
- Spa
- Fireplace/Heating
- Parking
US $255/Night
For 7 Nights US $1,785
300 ft²
2 Guests
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1 Bathroom
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4 Guests
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950 ft²
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2 Bedrooms
1 Bathroom
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950 ft²
6 Guests
2 Bedrooms
1 Bathroom
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Apartment
- Fireplace/Heating
- Balcony/Terrace
- Kitchen
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1100 ft²
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2 Bedrooms
2 Bathrooms
Family Friendly
Apartment
- Fireplace/Heating
- Balcony/Terrace
- Kitchen
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4 Guests
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US $146/Night
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4 Guests
1 Bedroom
1 Bathroom
Family Friendly
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- Fireplace/Heating
- Pool
- Breakfast
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8 Guests
5 Bedrooms
3 Bathrooms
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1200 ft²
6 Guests
3 Bedrooms
2 Bathrooms
Family Friendly
House
- Fireplace/Heating
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- Kitchen
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For 7 Nights US $3,041
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![Cozy Wine Country Home [ Lodging only . this is not an event venue ]](https://imgservice.rentbyowner.com/640x301/cozy-wine-country-home-us-defiance-ha-1214668827-0.jpg)
1340 ft²
5 Guests
3 Bedrooms
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- Balcony/Terrace
- Kitchen
US $227/Night
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