Discover Your Perfect Florence Vacation Homes

Best Vacation Homes in Florence

10.0
Exceptional
(28 Reviews)
800 ft² 5 Guests 2 Bedrooms 1 Bathroom
House
  • Fireplace/Heating
  • Parking
  • Air Conditioner
US $171/Night For 7 Nights US $1,198
10.0
Exceptional
(1 Review)
968.75 ft² 4 Guests 1 Bedroom 2 Bathrooms
Free Cancellation House
  • Fireplace/Heating
  • Parking
  • Internet
US $248/Night For 7 Nights US $1,734
9.2
Exceptional
(50 Reviews)
1 Bedroom 1 Bathroom
Couples Retreat Bed & Breakfast
  • Fireplace/Heating
  • Balcony/Terrace
  • Breakfast
US $124/Night For 7 Nights US $871
10.0
Exceptional
(24 Reviews)
6 Guests 2 Bedrooms 1 Bathroom
Family Friendly House
  • Fireplace/Heating
  • Balcony/Terrace
  • Pet Friendly
US $182/Night For 7 Nights US $1,274
10.0
Exceptional
(1 Review)
785.77 ft² 7 Guests 1 Bedroom 1 Bathroom
House
  • Fireplace/Heating
  • Parking
  • Internet
US $112/Night For 7 Nights US $784
10.0
Exceptional
(16 Reviews)
784 ft² 7 Guests 1 Bedroom 1 Bathroom
Family Friendly Cabin
  • Fireplace/Heating
  • Balcony/Terrace
  • Kitchen
US $151/Night For 7 Nights US $1,057
10.0
Exceptional
(9 Reviews)
570 ft² 5 Guests 2 Bedrooms 1 Bathroom
Family Friendly House
  • Fireplace/Heating
  • Kitchen
  • Parking
US $149/Night For 7 Nights US $1,042
10.0
Exceptional
(8 Reviews)
4 Guests 1 Bedroom 1 Bathroom
Family Friendly House
  • Fireplace/Heating
  • Balcony/Terrace
  • Kitchen
US $119/Night For 7 Nights US $835

Florence Luxury Rentals

New
4693.06 ft² 18 Guests 4 Bedrooms 4 Bathrooms
House
  • Fireplace/Heating
  • Parking
  • Internet
US $444/Night For 7 Nights US $3,110
New
1700.7 ft² 6 Guests 1 Bedroom 2 Bathrooms
Free Cancellation Apartment
  • Fireplace/Heating
  • Pet Friendly
  • Air Conditioner
US $433/Night For 7 Nights US $3,033
New
11 Guests 4 Bedrooms 2 Bathrooms
Group Friendly House
  • Fireplace/Heating
  • Air Conditioner
  • Internet
US $342/Night For 7 Nights US $2,397
10.0
Exceptional
(11 Reviews)
6 Guests 3 Bedrooms 2 Bathrooms
Family Friendly Apartment
  • Fireplace/Heating
  • Balcony/Terrace
  • Pet Friendly
US $320/Night For 7 Nights US $2,242
10.0
Exceptional
(3 Reviews)
4690 ft² 18 Guests 4 Bedrooms 3 Bathrooms
Family Friendly House
  • Fireplace/Heating
  • Balcony/Terrace
  • Kitchen
US $320/Night For 7 Nights US $2,241
9.8
Exceptional
(14 Reviews)
7 Guests 4 Bedrooms 2 Bathrooms
Family Friendly House
  • Fireplace/Heating
  • Balcony/Terrace
  • Kitchen
US $318/Night For 7 Nights US $2,229
9.6
Exceptional
(19 Reviews)
4000 ft² 13 Guests 4 Bedrooms 2 Bathrooms
Family Friendly Apartment
  • Hot Tub
  • Fireplace/Heating
  • Kitchen
US $299/Night For 7 Nights US $2,093
New
968.75 ft² 4 Guests 1 Bedroom 1 Bathroom
Free Cancellation Apartment
  • Fireplace/Heating
  • Pet Friendly
  • Air Conditioner
US $280/Night For 7 Nights US $1,960

Florence Pet Friendly Vacation Rentals

10.0
Exceptional
(7 Reviews)
4 Guests 2 Bedrooms 1 Bathroom
Family Friendly Apartment
  • Fireplace/Heating
  • Balcony/Terrace
  • Pet Friendly
US $255/Night For 7 Nights US $1,787
New
968.75 ft² 4 Guests 1 Bedroom 1 Bathroom
Free Cancellation Apartment
  • Fireplace/Heating
  • Pet Friendly
  • Air Conditioner
US $280/Night For 7 Nights US $1,960
8.0
Excellent
(781 Reviews)
1 Bathroom
Family Friendly Hotel
  • Pool
  • Breakfast
  • Pet Friendly
US $112/Night For 7 Nights US $783
10.0
Exceptional
(6 Reviews)
2 Guests 1 Bedroom 1 Bathroom
Family Friendly Apartment
  • Fireplace/Heating
  • Balcony/Terrace
  • Pet Friendly
US $140/Night For 7 Nights US $983
New
968.75 ft² 4 Guests 1 Bedroom 1 Bathroom
Free Cancellation Apartment
  • Fireplace/Heating
  • Pet Friendly
  • Air Conditioner
US $280/Night For 7 Nights US $1,960
10.0
Exceptional
(5 Reviews)
6 Guests 2 Bedrooms 2 Bathrooms
Family Friendly House
  • Fireplace/Heating
  • Balcony/Terrace
  • Pet Friendly
US $222/Night For 7 Nights US $1,556
10.0
Exceptional
(3 Reviews)
2 Guests 1 Bedroom 1 Bathroom
Family Friendly Apartment
  • Fireplace/Heating
  • Balcony/Terrace
  • Pet Friendly
US $184/Night For 7 Nights US $1,287
10.0
Exceptional
(2 Reviews)
2 Guests 1 Bedroom 1 Bathroom
Family Friendly Apartment
  • Fireplace/Heating
  • Pet Friendly
  • Kitchen
US $177/Night For 7 Nights US $1,236

Florence Large Vacation Homes

9.8
Exceptional
(26 Reviews)
3640 ft² 11 Guests 4 Bedrooms 2 Bathrooms
Family Friendly House
  • Fireplace/Heating
  • Balcony/Terrace
  • Kitchen
US $224/Night For 7 Nights US $1,567
New
204.51 ft² 8 Guests 115 Bedrooms 3 Bathrooms
Family Friendly Cabin
  • Private Pool
  • Hot Tub
  • Fireplace/Heating
US $96/Night For 7 Nights US $670
10.0
Exceptional
(17 Reviews)
7 Guests 2 Bedrooms 1 Bathroom
Family Friendly Villa
  • Fireplace/Heating
  • Pool
  • Balcony/Terrace
US $213/Night For 7 Nights US $1,491

Why Choose Rent By Owner for your Florence Vacation Rental Homes?

What makes our Vacation Rentals special?

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Verified Listings
Book with confidence knowing every property meets our quality and safety standards.
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Unbeatable Value
Enjoy competitive pricing with no hidden fees, providing exceptional value for every stay.
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Diverse Options
From cozy cabins to luxurious villas, find a rental that suits your style and needs.

Best Times to Visit Florence

When should you plan your Vacation Rentals stay?

Choosing the right time to vacation here can enhance your experience, as the region offers distinct advantages during different seasons, making it essential to plan your stay accordingly for an optimal visit.

Peak Season Highlights

spring
Spring (March to May)

During spring, this area experiences pleasant weather, making it an ideal time for exploring the region's natural beauty and outdoor activities.

Average Temperature Daytime: 65°F to 75°F - Nighttime: 45°F to 55°F
autumn
Fall (September to November)

Autumn offers cooler temperatures and vibrant foliage, providing a picturesque setting perfect for enjoying the outdoors and seasonal events.

Average Temperature Daytime: 60°F to 70°F - Nighttime: 40°F to 50°F

Off-Season Highlights

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Summer (June to August)

In summer, the area sees warmer days that are great for water-based activities and enjoying longer daylight hours, though some might find it busier during this time.

Average Temperature Daytime: 80°F to 90°F - Nighttime: 60°F to 70°F
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Winter (December to February)

Winter tends to be quieter, with cooler temperatures ideal for those seeking a peaceful retreat away from peak crowds.

Average Temperature Daytime: 35°F to 45°F - Nighttime: 20°F to 30°F

Weekly Weather Forecast for Florence

Booking Steps

01

Search Properties

Use our filters to find the right property that fits your needs.
02

Select a Rental

Click on your preferred listing to view details, amenities, and pricing.
03

Book Online

Follow the link to finalize your reservation directly on the partner’s website.

Indoor Features

  • Fully-equipped kitchens with modern appliances
  • Comfortable living areas with flat-screen TVs
  • Free Wi-Fi for staying connected
  • Air conditioning and heating for year-round comfort
  • In-unit washers and dryers for convenience
  • Luxurious bedrooms with premium bedding
  • Spa-like bathrooms with soaking tubs or walk-in showers

Outdoor Amenities

  • Enjoy outdoor seating areas perfect for relaxing and dining amidst scenic surroundings.
  • Take advantage of private patios or decks that provide a peaceful spot to unwind after exploring the region.
  • Make use of spacious yards or gardens ideal for outdoor activities or simply enjoying the fresh air.
  • Benefit from access to outdoor grills or barbecue facilities to enhance your outdoor dining experiences.
  • Discover well-maintained walking paths or trails nearby, perfect for morning strolls or nature walks.
  • Relax in inviting outdoor fire pits, great for cozy evenings with family or friends.
  • Utilize available picnic tables or shaded areas to enjoy meals outdoors in the pleasant climate of this destination.
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Family Activities

  • Missouri River Outpost: Enjoy family-friendly fishing, kayaking, and picnicking along the scenic Missouri River that runs through the region.
  • Florence Nature Preserve: Explore miles of hiking and biking trails perfect for outdoor adventures with your loved ones in this peaceful natural setting.
  • Local Heritage Museum: Discover the area's history through engaging exhibits and interactive displays that are ideal for family educational outings.
  • Community Park and Playground: Spend quality time at the local park, where kids can enjoy modern playground equipment and open spaces for sports and fun activities.
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Adult Activities

  • Exploring local wineries and vineyards: Discover the region’s renowned wineries for tastings and tours that showcase the area's rich winemaking tradition.
  • Enjoying outdoor recreation at nearby parks: Take advantage of scenic parks and trails perfect for hiking, picnicking, or relaxing amid nature in this picturesque destination.
  • Visiting historic landmarks and museums: Immerse yourself in the area's history by exploring well-preserved landmarks and engaging museums for a cultural experience.
  • Sampling regional cuisine at local eateries: Indulge in authentic flavors at cozy restaurants and cafes that highlight the region’s culinary specialties.

Florence Travel Tips

How Can You Make the Most of Your Stay?

  • Explore Local Cuisine: Delight in trying regional specialties at local eateries to experience the authentic flavors of this destination.
  • Plan Outdoor Activities: Take advantage of scenic parks and outdoor spaces near your vacation rentals for memorable adventures and relaxation.
  • Discover Hidden Gems: Ask your hosts or locals for lesser-known spots that offer unique views and a peaceful atmosphere away from the typical tourist routes.
  • Schedule Flexible Sightseeing: Keep your itinerary adaptable to fully enjoy spontaneous discoveries and the charming ambiance of the area.

Transportation Options

  • Personal Vehicles: Renting or bringing your own vehicle offers flexible and convenient transportation around this region, allowing you to explore at your own pace.
  • Local Taxis and Rideshare Services: Taxis and rideshare options like Uber or Lyft provide easy access for quick trips within the area, ensuring reliable transportation during your stay.
  • Public Transit: The local bus system operates throughout the region, offering budget-friendly travel options for exploring here without the need for a car.
  • Bicycle Rentals: Cycling is a popular way to experience the area's scenic routes, with bike rentals readily available for a healthy and eco-friendly journey.

Local Customs Options

  • Southern Hospitality: You can expect a warm welcome and friendly interactions, which are traditional in this region of Missouri known for its genuine Southern hospitality.
  • Local Festivities: Participating in community events like local fairs or celebrations here offers a glimpse into the area’s rich cultural traditions and lively customs.
  • Traditional Cuisine: Savor regional flavors by trying dishes that reflect the area's culinary heritage, often shared during family gatherings and local festivals.
  • Respect for Heritage: When visiting historic sites or engaging with residents, you'll notice a strong respect for local history and customs that shape daily life here.

Florence Vacation Rental Frequently Asked Questions

1. What are the top vacation rentals in Florence?

2. Which vacation homes in Florence are best for families?

If you are looking for a family-friendly vacation home in Florence, check out one of the following properties as all are highly-rated places to stay with excellent review for families or groups staying in Florence:

3. How many Rentbyowner vacation rentals are available in Florence?

Currently, the total number of properties listed by Rent By Owner in 2026 is over 88 in the Florence area, and still counting. By aggregating listings from multiple websites, Rent By Owner offers an immense amount of choice of the best RBO properties in Florence. 

4. What is the cancellation policy for vacation rentals in Florence, Missouri?

The cancellation policy varies depending on the listing you choose. You should review the specific terms outlined in the rental listing or contact the property owner directly to understand the details and any applicable fees before booking.

5. Are there any additional fees I should be aware of when booking a vacation rental here?

Additional fees such as cleaning fees, service charges, or security deposits are often listed on the property page. It's advisable to read the full listing details thoroughly or reach out to the host for clarification before confirming your reservation.

6. How do I ensure my reservation is secure and confirmed?

Reservations are typically secured through the booking platform’s secure system once you complete the payment process. Confirm your booking directly with the host if needed, and keep all correspondence for reference.

7. What amenities are usually included in vacation rentals in this part of the region?

Amenities vary by property but commonly include essentials like Wi-Fi, parking, kitchen facilities, and laundry options. To confirm what’s included, review the property description carefully or contact the owner for specific inquiries.

8. What should I know about check-in and check-out procedures?

Check-in and check-out details are specified in each listing. Many hosts use self-check-in options for flexibility. It’s best to coordinate directly with the property owner if you have special requests or need further guidance.

Florence Top Rated Vacation Rentals

9.2
Exceptional
(616 Reviews)
1 Bathroom
Family Friendly Hotel
  • Fireplace/Heating
  • Pool
  • Breakfast
US $129/Night For 7 Nights US $900
9.2
Exceptional
(601 Reviews)
1 Bathroom
Family Friendly Hotel
  • Hot Tub
  • Pool
  • Balcony/Terrace
US $154/Night For 7 Nights US $1,081
9.0
Exceptional
(86 Reviews)
301.39 ft² 1 Bathroom
Family Friendly Hotel
  • Private Pool
  • Fireplace/Heating
  • Pool
US $120/Night For 7 Nights US $838
8.6
Fabulous
(266 Reviews)
1 Bathroom
Family Friendly Hotel
  • Pool
  • Breakfast
  • Kitchen
US $132/Night For 7 Nights US $924
8.6
Fabulous
(190 Reviews)
226.04 ft² 1 Bathroom
Hotel
  • Private Pool
  • Fireplace/Heating
  • Pool
US $105/Night For 7 Nights US $735
7.7
Very Good
(148 Reviews)
367.05 ft² 1 Bathroom
Hotel
  • Private Pool
  • Oceanfront
  • Fireplace/Heating
US $120/Night For 7 Nights US $839
7.4
Very Good
(11 Reviews)
1 Bathroom
Couples Retreat Hotel
  • Pool
  • Parking
  • Air Conditioner
US $101/Night For 7 Nights US $704
6.2
Good
(330 Reviews)
1 Bathroom
Family Friendly Hotel
  • Pool
  • Balcony/Terrace
  • Kitchen
US $56/Night For 7 Nights US $394